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Samuele Lillini (Preclinical Area)
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Instruments
Animal Model Unit
Infrastructure of the Research & Early Development and R&D Technology (Preclinical) Business Units located in Naples
expertise and know-how of Dompé researchers in the characterization of new products and their formulations to define the safety profile (toxicology studies) of the best candidates (prototypes) to be launched into clinical development
Data Storage and Deep Learning
The Exscalate platform for structure-based virtual screening developed by Dompé researchers and designed to accelerate drug discovery and lead optimization processes
featuring high-precision simulations supported by advanced computing capabilities in bioinformatics and modeling to identify promising molecules and optimize therapeutic strategies
Procedures
Process: characterization of neurotrophins in representative models of diseases
Procedure: development of in vitro and in vivo models useful for new potential clinical applications of neurotrophins in the field of treating diseases with high unmet clinical need, with particular attention to severe and acute diseases of the central nervous system, to advance the development of the most promising candidates, generate data from selected models, and acquire new knowledge
GEMINI 
GENESI 
