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University of Naples Federico II

Technical Contact

Maria Iannone
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Instruments

Organ on Chip

  • Advanced 3D culture platforms and neuronal co-cultures for the simulation of somatosensory circuits and nocicetive pathways
  • Microfluidic systems and biomimetic matrices for the reproduction of pathological microenvironments (neuroinflammation; neuropathies; chronic pain)
  • In vitro drug screening platforms on neuronal and glial models

Procedures

  • Development of in vitro experimental models for the multifactorial simulation of CNS and PNS diseases
  • Implementation of drug screening platforms for the evaluation of therapeutic response through electrophysiological, molecular, and behavioral analysis
  • Development of computational pipelines for the automated extraction of biological features (morphological, molecular, electrophysiological)

Partners